16.08.2025
Bioactive Peptides
Context:
Research by the Institute of Advanced Study in Science and Technology (IASST), Guwahati, indicates that bioactive peptides present in fermented foods may provide health benefits specific to different population groups. This opens avenues for personalised nutrition approaches in India.
Bioactive Peptides:
- Small fragments of proteins, usually composed of 2–20 amino acids.
- Released during the fermentation of foods like yogurt, idli, miso, kimchi, natto, and fermented fish.
- Exhibit antimicrobial properties, helping fight harmful microbes.
- Have antioxidant effects, reducing oxidative stress in the body.
- Can lower blood pressure, contributing to cardiovascular health.
- Show immune-modulatory activity, supporting and regulating the immune system.
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Key Characteristics:
- Mechanism of Action: Peptides interact with biological molecules through electrostatic interactions, hydrogen bonding, and hydrophobic effects.
- Health Implications: They influence cardiovascular health, metabolism, and immune system function.
- Population-Specific Effects: Their effectiveness may vary due to genetic differences (e.g., ACE or IL-6 gene variants), gut microbiome composition, and dietary patterns.
- Research Approaches: Advanced omics techniques are recommended for a detailed understanding of their effects.
Significance:
- Public Health Relevance: Can be incorporated into dietary recommendations to prevent or manage hypertension, diabetes, and immune-related disorders.
- Cultural Importance: Supports the global recognition of India’s traditional fermented foods in modern nutritional science.
Conclusion:
Bioactive peptides from fermented foods hold significant potential for improving population-specific health outcomes in India. Integrating them into dietary guidelines and personalised nutrition plans can strengthen preventive healthcare, promote traditional diets, and support overall well-being.