Kindlins
02.08.2024
Kindlins
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For Prelims: About Kindlins |
Why in the news?
A recent study of kidlins has revealed a novel pathway to cancer treatment.
About Kindlins:
- These are adapter proteins that exist inside the cells attached to the cell membranes of almost all types of cells in vertebrates.
- The Kindlin family of proteins contains three members: Kindlin 1, 2, 3 with distinct amino acid sequences and tissue distribution.
- They transfer extracellular mechanical cues to biochemical signals inside the cells and play a pivotal role in conveying extracellular signals by physically interacting with structural proteins, receptors and transcription factors, triggering a cascade of chemical signals within the cell.
- Structural disruptions in these proteins can have a global impact on mechano chemical signaling, leading to disruptions in the state of balance among all the body systems needed for the body to survive and function correctly.
- Kindlins may undergo mutations under the influence of innumerable chemical and physical carcinogens like nicotine, ultraviolet rays and many more.
- Mutated Kindlin can potentially disrupt global mechanical homeostasis within cells.
Source: PIB
Ques :- The term “kindlins”, recently seen in the news, refers to:
A.types of viruses which infect humans
B.newly discovered dwarf stars
C.new types of plant cells
D.adapter proteins that exist inside the cells
Answer D